Astrid Gillich, Ph.D. - Calico Skip to content 0% Calico Research & Technology Research & Technology Publications Drug Development Drug Development Patients Partnering Leadership Careers Job Openings PostDoc Program Mission and Values Leadership Research & Technology Drug Development Patients Partnering Collaborator Profiles People Publications News & Media Press Releases Calico Stories Life at Calico Careers Job Openings PostDoc Program Contact Us Back to Senior R&D Staff Astrid Gillich, Ph.D. Principal Investigator Astrid investigates cellular processes underlying aging and age-related diseases in the lung and how they can be manipulated to maintain or restore organ function. About Astrid’s research focuses on alveoli, the sites of gas exchange in the lung. Using genetic, transcriptomic and single-cell approaches, her lab explores how alveolar cells become altered due to aging and age-related diseases. By precisely controlling and manipulating cell behaviors, interactions and functions, she hopes to find ways to prevent or reverse these changes and associated disease pathologies in order to restore gas exchange. Prior to Calico, Astrid was a postdoctoral fellow in the lab of Mark Krasnow at Stanford University where she defined the three-dimensional cellular structure of alveoli and discovered a novel mechanism of alveolar formation. Her research demonstrated that the alveolar capillary endothelium is made up of two intermingled cell types with distinct structures and functions — expansive aerocytes that are specialized for gas exchange, and general capillary cells that function as progenitors in alveolar capillary maintenance and repair. Education: Postdoc in Lung Biology, Stanford University Ph.D. in Stem Cell Biology, University of Cambridge M.Sc. and B.Sc. in Biotechnology, University of Natural Resources and Life Sciences, Vienna Featured Publications: Capillary cell-type specialization in the alveolus A molecular cell atlas of the human lung from single-cell RNA sequencing Awards: American Heart Association Postdoctoral Fellowship, 2016 Erwin Schrödinger Fellowship, Austrian Science Fund, 2012 See Other Senior R&D Staff Profiles Brian Feng, Ph.D Director, Cellular Phenotyping Ari Firestone, Ph.D. Principal Investigator Daniel Gottschling, Ph.D. Distinguished Fellow Nathan Guz, Ph.D. Head of Chemistry, Manufacturing, and Controls (CMC) PREVIOUS BIO NEXT BIO About Us Research & Technology Drug Development Leadership Partnering Our Story Life at Calico Resources Publications Calico Stories News & Media Patients Contact Us Contact Us Join Us Follow Us X LinkedIn Privacy Policy Notice at Collection Terms of Use Code of Conduct 2026 Calico Life Sciences LLC. All rights reserved. Close