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Serial cardiorespiratory exercise testing in patients with congenital heart disease T Reybrouck  1 , R Rogers, M Weymans, M Dumoulin, M Vanhove, W Daenen, L Van der Hauwaert, M Gewillig Affiliations Expand Affiliation 1 Department of Cardiovascular Rehabilitation, Gasthuisberg University Hospital, Leuven, Belgium. PMID: 8529676 DOI: 10.1007/BF01959785 Item in Clipboard Serial cardiorespiratory exercise testing in patients with congenital heart disease T Reybrouck et al. Eur J Pediatr. 1995 Oct. Show details Display options Display options Format Abstract PubMed PMID Eur J Pediatr Actions Search in PubMed Search in NLM Catalog Add to Search . 1995 Oct;154(10):801-6. doi: 10.1007/BF01959785. Authors T Reybrouck  1 , R Rogers, M Weymans, M Dumoulin, M Vanhove, W Daenen, L Van der Hauwaert, M Gewillig Affiliation 1 Department of Cardiovascular Rehabilitation, Gasthuisberg University Hospital, Leuven, Belgium. PMID: 8529676 DOI: 10.1007/BF01959785 Item in Clipboard Cite Display options Display options Format AbstractPubMedPMID Abstract Aerobic capacity of patients with different forms of congenital heart disease was serially evaluated in 79 patients and the evolution was correlated with the lesion and the level of daily activity. The patients were divided into six groups: patients with a small ventricular septal defect (VSD) with mini shunt (n = 14), mild pulmonary valve stenosis with gradient < 40 mm Hg (PS) (n = 12), mild to moderate aortic valve stenosis (gradient 36 +/- 17 mmHg) (AS) (n = 12), patients 4.7 +/- 2.1 years after repair of tetralogy of Fallot (PO-TF) (n = 16), patients 2.2 +/- 2.9 years after closure of a high flow/high gradient VSD (PO-VSD) (n = 13), and patients 2.6 +/- 1.7 years after Fontan repair (Fontan-PO) (n = 12). Aerobic capacity was assessed by determination of the ventilatory anaerobic threshold (VAT). VAT reflects the highest aerobic exercise level prior to a disproportionate increase of CO2 and ventilation relative to O2 uptake; it is independent of patient motivation. Data are expressed as percentage of normal O2 uptake at VAT, determined in 234 age/gender matched controls. The habitual level of physical activity was assessed by a standardised questionnaire. Aerobic capacity in all subgroups of patients, even with very mild defects, was at or below the lower limit of normal. Children left unrestricted from physical exercise (VSD, PS, PO-VSD) had no change over the study period. However, aerobic capacity of patients with medically imposed physical restrictions (AS) and significant residual haemodynamic lesions (PO-TF, Fontan) decreased with age.(ABSTRACT TRUNCATED AT 250 WORDS) PubMed Disclaimer References Pediatr Cardiol. 1986;7(1):19-24 - PubMed Eur J Appl Physiol Occup Physiol. 1985;54(3):278-84 - PubMed J Thorac Cardiovasc Surg. 1980 Oct;80(4):582-93 - PubMed Mayo Clin Proc. 1989 Dec;64(12):1489-97 - PubMed Eur J Appl Physiol Occup Physiol. 1989;58(8):803-7 - PubMed Show all 23 references Publication types Research Support, Non-U.S. Gov't Actions Search in PubMed Search in MeSH Add to Search MeSH terms Adolescent Actions Search in PubMed Search in MeSH Add to Search Anaerobic Threshold / physiology Actions Search in PubMed Search in MeSH Add to Search Carbon Dioxide / blood Actions Search in PubMed Search in MeSH Add to Search Child Actions Search in PubMed Search in MeSH Add to Search Child, Preschool Actions Search in PubMed Search in MeSH Add to Search Disability Evaluation Actions Search in PubMed Search in MeSH Add to Search Exercise Test* Actions Search in PubMed Search in MeSH Add to Search Female Actions Search in PubMed Search in MeSH Add to Search Follow-Up Studies Actions Search in PubMed Search in MeSH Add to Search Fontan Procedure Actions Search in PubMed Search in MeSH Add to Search Heart Defects, Congenital / classification Actions Search in PubMed Search in MeSH Add to Search Heart Defects, Congenital / physiopathology* Actions Search in PubMed Search in MeSH Add to Search Heart Defects, Congenital / surgery Actions Search in PubMed Search in MeSH Add to Search Hemodynamics / physiology* Actions Search in PubMed Search in MeSH Add to Search Humans Actions Search in PubMed Search in MeSH Add to Search Male Actions Search in PubMed Search in MeSH Add to Search Oxygen / blood Actions Search in PubMed Search in MeSH Add to Search Postoperative Complications / classification Actions Search in PubMed Search in MeSH Add to Search Postoperative Complications / physiopathology Actions Search in PubMed Search in MeSH Add to Search Substances Carbon Dioxide Actions Search in PubMed Search in MeSH Add to Search Oxygen Actions Search in PubMed Search in MeSH Add to Search LinkOut - more resources Medical ClinicalTrials.gov MedlinePlus Health Information Miscellaneous NCI CPTAC Assay Portal [x] Cite Copy Download .nbib .nbib Format: AMA APA MLA NLM Send To Clipboard Email Save My Bibliography Collections Citation Manager [x] NCBI Literature Resources MeSH PMC Bookshelf Disclaimer The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 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